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![]() R., et al., “Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery”, Cell, vol. Thakkar, H., et al., “Pro-survival Function of Akt/Protein Kinase B in Prostate Cancer Cells”, The Journal of Biological Chemistry, vol. Stål, O., et al., “Akt kinases in breast cancer and the results of adjuvant therapy”, Breast Cancer Res, vol. Reuveni, H., et al., “Toward a PKB Inhibitor: Modification of a Selective PKA Inhibitor by Rational Design”, Biochemistry, vol. N., et al., “NF-KB activation by tumour necrosis factor requires the Akt serine-threonine kinase”, Nature, vol. 1004-1010, 1996.Ĭheng et al., The Akt/PKB pathway: molecular target for cancer drug discovery, Oncogene Rev. Simone, Oncology: Introduction, Cecil Textbook of Medicine, 20th Edition, vol. N-4-(6- (HETEO) ARYL-PYRIMIDIN-4-YLAMINOPHENYL) -BEZENESULFONAMIDES AS KINASE INHIBITORS PHARMACEUTICALLY ACTIVE 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF PROTEIN KINASES HETEROARYL AMINES AS GLYCOGEN SYNTHASE KINASE 3BETA INHIBITORS (GSK3 INHIBITORS)ĬOMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF AMYLOID-β PEPTIDE-RELATED DISORDERSĢ,4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTSĬYTOKINE, ESPECIALLY TNF-ALPHA, INHIBITORSĤ-PYRIMIDINAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND RELATED METHODSĪMIDE DERIVATIVES AS GLYCOGEN SYNTHASE KINASE 3-BETA INHIBITORS IRREVERSIBLE INHIBITORS OF TYROSINE KINASES ![]()
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